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Mohammed Adam
Bilow

what role does greater permeability of capillaries play in the inflammatory response

what role does greater permeability of capillaries play in the inflammatory response
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  1. The greater permeability of capillaries plays a crucial role in the inflammatory response. During an inflammatory response, various chemical mediators are released, such as histamine, bradykinin, and leukotrienes. These mediators cause the local blood vessels, including capillaries, to become more permeable.

    As the capillaries become more permeable, the gaps between the endothelial cells that line the capillary walls widen. This allows fluid, proteins, and immune cells to leak out of the blood vessels and into the surrounding tissues. The increased blood flow and accumulation of immune cells in the inflamed area help to fight off any invading pathogens and repair any damaged tissues.

    The increased permeability of capillaries also allows for the migration of white blood cells, such as neutrophils and monocytes, into the inflamed tissue. These cells are essential for the immune response, as they can engulf and destroy invading pathogens and damaged cells.

    In summary, the greater permeability of capillaries is a critical component of the inflammatory response, allowing for the migration of immune cells and other essential components into the inflamed tissue to fight off pathogens and repair damaged tissues.

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